The City of Lawton is located in Southwest Oklahoma, in Comanche County, 90 miles southwest of Oklahoma City on Interstate 44. The Fort Sill Army post is located just to the north and adjacent to Lawton, and is part of the Lawton community. The Wichita Mountains National Wildlife Refuge is located to the north and west of Lawton, and is a popular area attraction.

Lawton is the third largest city in Oklahoma, and is on Forbes' List of the Best Small Places for Business and Careers .